Significance of the determination of DNA load of drug-resistant mycoplasma pneumoniae and 23sRNA gene mutation locus in children

Purpose: To determine the significance of detection Mycoplasma pneumoniae (MP)-DNA load and 23sRNA gene mutation locus in children with drug-resistant MP pneumonia. 
 Methods: A total 158 pneumonia received drug sensitivity tests. The patients were divided into resistance group non-resistance group. MP-DNA index (MPLI) rate at 2063 assessed compared between two groups: MPLI-negative MPLI-positive group, based on whether MPLI was greater than 6.12. association all as well clinical indicators analyzed. Results: lower that In duration disease, defervescence time, disappearance time cough expectoration, chest opacity, length stay longer those while proportion cases extrapulmonary complications white blood cell (WBC) count higher (p < 0.05). opacity mutation-positive mutation-negative Conclusion: is Furthermore, low mutations are associated symptoms other indicators.